About Our Main Research Areas

In living cells, proteins rarely act in isolation; instead, they interact dynamically with one another to execute their functions. Accordingly, proteins associate with specific binding partners at appropriate times and places to form functional complexes that drive diverse cellular processes. Research in my laboratory focuses on understanding how proteins assemble into stable complexes with their interaction partners and how these complexes execute their activities within signaling pathways and multi-protein assemblies. In particular, we investigate how micron-scale microtubule arrays are organized and regulated to support mitosis, ciliogenesis, and neuronal maturation.

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Through these studies, we aim to uncover the mechanistic links between cytoskeletal organization and essential cellular functions. Beyond fundamental cell biology, our research also seeks to elucidate the molecular mechanisms underlying cancer cell proliferation and drug resistance, with a particular emphasis on how cytoskeletal systems contribute to these pathological processes.